Independent quality controls allow laboratories to validate calibrations, monitor accuracy and precision, and reduce interlaboratory variation
Cytokine assay results vary depending on the assay manufacturer and the assay method.
Good quality control is essential for cytokine assays, however high quality cytokine controls can be difficult to obtain.
Randox Laboratories tri-level cytokine controls are available now, for cytokine assays and high-sensitivity cytokine assays.
Randox cytokine controls are ideal for multiplex assays and for multi-centre clinical trials.
Many cytokine assays suffer from inconsistent accuracy and poor precision.
In addition, different manufacturers' assays produce markedly different results depending on the production process and the assay method.
Using kit controls can add to the problem.
Kit controls are often manufactured using the same materials and production methods as the kit components, then optimised for a specific instrument.
The result is that kit controls can actually conceal problems arising from the reagents, calibrators or instrument.
Cytokine assays should be controlled using an independent quality control to monitor accuracy and precision.
Randox independent quality controls are designed for use with a wide range of methods and instruments.
Cytokines are signalling proteins, released primarily by immune cells.
Cytokines are implicated in a number of diseases.
The complexity of the cytokine signalling network and the roles played by different cytokines is critical to understanding both normal and pathological processes.
This has led to the emergence of multiplex assays that give a 'snapshot' of multiple cytokines in a single sample.
Quality control is particularly important for multiplex assays due to the greater demands of performing several assays in a single procedure.
