Adhesion molecule biochip arrays from Randox allow simultaneous detection of up to five adhesion molecules in a single undivided patient sample - ideal for a multitude of research purposes
Adhesion molecules are proteins capable of binding to other molecules on the surface of an adjacent cell or part of the extracellular matrix.
They play a key role in development and immune processes for example, in the functions of leukocytes, where they mediate contact with blood vessels endothelia.
Adhesion molecules can be found in the cell membrane or as soluble proteins in the blood.
Altered levels of these proteins have been found in pathological states including cardiovascular disease, stroke and cancer.
Biochip arrays utilise biochip array technology, which is based on Elisa principles of sandwich or competitive immunoassays.
The 9x9mm biochip acts as a reaction platform, with five adhesion molecule specific antibodies attached at pre-defined sites on the surface.
Up to five analytes can be measured simultaneously using just 25ml of patient sample and either human serum or plasma can be tested.
