Shimadzu Scientific Instruments has updated its line of Axima Maldi Tof mass spectrometers (MS) with three new systems to meet the needs of researchers with varying applications and budgets
The Axima Performance mass spectrometer provides the pinnacle of performance for high-energy MS/MS interrogation of proteomics, biological and organic samples.
These include peptides, polymers, oligonucleotides, SNPs, metabolites, and carbohydrates.
It also demonstrates outstanding performance in the analysis of high-mass species, such as intact proteins.
In reflectron mode high-resolution MS data is generated for peptide mass fingerprinting and complex mixture analysis.
Full automation, advanced calibration algorithms, data-dependent workflows and application-centric software help users achieve maximum results with minimal user input.
Software packages include proteomics, polymer and copolymer analysis, LC-Maldi, biomarker discovery and tissue imaging.
Shimadzu designed the Axima Confidence and Assurance instruments with general analytical and life-science laboratories in mind.
Both systems are affordable, robust options for routine sample analysis performed manually or automatically.
Positive- and negative-ion modes are standard, allowing users full flexibility.
Shimadzu also incorporated a patented beam blanker to optionally remove unwanted low-mass ions and prevent detector saturation.
The Confidence Maldi MS offers reliable mass information and MS/MS-derived structural detail.
A linear mode enables outstanding levels of analysis of high-molecular weight samples.
The reflectron mode, incorporating the patented curved-field reflectron, provides high resolution and mass accuracy.
Confidence software packages are available specifically for proteomics experiments, LC-Maldi, polymer and copolymer analysis, biomarker discovery, tissue imaging and oligonucleotide/primer analysis.
The Assurance Maldi MS is a linear-only Maldi-Tof mass spectrometer designed for reliable mass information.
It is suited for high-throughput QA/QC analysis of oligonucleotide/primers, synthetic peptides/proteins, polymers, and other small molecules.
The system's flexibility makes it ideal for protein profiling, tissue imaging, biomarker discovery, and single nucleotide polymorphisms.
All Axima Maldi-Tof systems are fully integrated with robotic sample preparation devices, including the AccuSpot Maldi plate spotter and CHIP chemical printer.
This integration with the CHIP, proprietary display programs and BioMap software creates a powerful platform for tissue imaging.
Flexible target formats range from 48-well microscope slide format targets to 384-well microtitre plate targets.
Axima systems are fully supported throughout their lifetime using sophisticated web-based service diagnostics and the capability of real-time remote monitoring.