Abd Serotec is to present ways for standardisation of autoimmune tests using antibodies generated using its Hucal technology at the 6th International Congress on Autoimmunity on 11-12 September.
The detection of human antibodies in patient sera in various formats or isotypes lies at the heart of a broad range of immunodiagnostic assays in autoimmunity and infectious diseases.
For the majority of these tests, assay control reagents and calibrators are needed, but their availability and quality often do not meet the requirements of the diagnostic industry.
Today, patient sera are predominantly used and are considered the 'gold standard'.
The problems associated with the use of such sera include the need to repeatedly calibrate the assay due to variations in product quality, limited quantities and the potential of contamination with harmful substances such as viruses.
Abd Serotec considers calibrators and controls based on its fully in vitro-based Hucal technology as an offering for these applications based on the technology's flexibility in antibody generation and the possibility to create human monoclonal antibodies of any isotype.
Several diagnostic customers have already ordered Hucal-based antibodies for these applications.
