Meridian Life Science has released antigens for the Herpes Simplex Virus (HSV).
Herpes Simplex Virus-2 (HSV-2 GG, native) is affinity purified from virus strain G.
It is a serotype specific antigen with high specificity and little or no cross-reactivity to HSV-1 antigens.
Herpes Simplex Virus-1 is a Patton strain antigen produced in Saccharomyces cerevisiae with the amino acid sequence 1-190 (N-Terminal).
Advantages over E coli produced antigens include glycosylation and better folding.
Herpes Simplex Virus-2 (HSV-2 GG, recombinant) is also produced in Saccharomyces cerevisiae.
The amino acid sequence is 343-649, a unique sequence that is not present in HSV-1.
Advantages over E coli produced antigens include glycosylation and better folding.
Herpes Simplex Virus (HSV) is a widespread infectious pathogen of humans.
HSV infections may be accompanied by vesicular eruptions of the skin or mucous membranes.
Both HSV Types 1 and 2 can cause severe clinical diseases including keratoconjunctivitis, meningitis, encephalitis, eczema herpeticum, genital herpes and generalized infection.
Research studies, utilising native or recombinant HSV antigens along with HSV antibodies, are focused on understanding this infectious agent and its relationship to other diseases.
