Thermo Fisher Scientific has introduced Thermo Scientific PocketTip DARTs tips, enabling nanolitre-volume dispensing on Thermo Scientific Matrix automated systems.
An internally moulded capillary pocket allows the transfer of 50-500 nanolitres of concentrated sample compounds suspended in Dimethyl Sulphoxide (DMSO) directly to assay plates, saving time, reagents and labware, as well as improving data quality with in-tip mixing.
PocketTip DARTs tips introduce an easy, low-risk and reliable method, to change the way in which current instrumentation performs critical liquid handling tasks.
Through aspiration, the capillary pocket fills with the specified amount of compound solution and facilitates soft in-tip mixing of sample and assay material, removing time-consuming intermediate dilution steps and adding further function to the existing instruments.
The face seal of the DARTs tip minimises tip-to-tip height variations for consistent dispensing.
This pipetting method makes it possible to perform assays quicker, reduce reagent costs and prevent compound precipitation for more accurate and precise results.
PocketTip DARTs tips are suitable for all secondary compound screening applications, such as selectivity assays, potency determinations, cell- and enzyme-based assays and PCR primer dilutions.