Copley has released a cascade impactor for abbreviated impactor measurements that accelerates inhalation-product testing.
Multi-stage cascade impaction provides aerodynamic particle size information for inhaled drug products and is a standard requirement of regulators.
The MSP Fast Screening Impactor (FSI) is based around the Next Generation Impactor pre-separator.
The FSI is coupled with a fine particle collector and a USP/Ph.Eur induction port.
It focuses on the fine particle fraction: the sub five-micron portion of the dose that is considered to deposit deep in the lung.
Large boluses impinge onto a liquid trap while a single precision stage generates a cut-off diameter of five microns.
The fine particle dose is then trapped on a glass fibre filter in the fine particle collector.
The FSI is high capacity, has low internal losses and low carryover.
A range of inserts provide a five-micron cut-off diameter at defined flow rates within the 30 to 100 L/min range routinely used for testing metered dose and dry powder inhalers.
An additional 10-micron insert is available specifically for nasal spray testing.
