A range of Biovyon C18 silica columns and microplates has been introduced by Porvair Filtration Group for use in low-volume solid-phase extraction (SPE) assays.
Traditional packed bed SPE columns and microplates perform relatively inefficiently when using the shallow sorbent beds necessary to get good recovery from smaller sample volumes.
Immobilising the C18 sorbent within the porous Biovyon polymer, Porvair has created a high-surface-area matrix intended to provide good control of flow rate.
The immobilised C18 sorbent cannot form liquid channels and does not require inert frits to support it, thereby minimising hold-up volume.
The combination of these attributes has enabled Porvair to introduce a range of SPE columns and microplates that provide higher consistency and greater recoveries for small sample volume assays.
Biovyon C18 is initially being offered in 96-well microplates as a 10mg-per-well loading suitable for low-volume bio-assay preparation and clean-ups.
In the popular 1ml cartridge format, Biovyon C18 is available in a choice of 12.5mg, 25mg and 50mg loadings to suit different applications.
Biovyon is made from a pharmaceutical-grade polyethylene material.
Using novel Activyon technologies, Porvair Filtration Group is pioneering chemical modification and activation of Biovyon to create a family of materials that are intended to represent opportunities for the simple, robust and ultra-fast purification of biological materials and molecules.
The Biovyon family includes columns and microplates for high-performance SPE and antibody purification.