Beckman Coulter introduces the Gallios flow cytometry system, which has been developed for the research and biopharmaceutical markets.
The multi-colour, multi-laser Gallios is the first in a series of key flow cytometry instrument, software and reagent releases that Beckman Coulter plans to announce this year.
A particular emphasis on optical and electronics design, combined with automation and software tools, allows Gallios to enhance the efficiency and analytical capabilities of flow cytometry laboratories, claims Beckman Coulter.
Specially developed electronics provide accurate digital signal processing at high event rates over a wide dynamic range of fluorescence intensities.
The system is packaged in a compact analyser that delivers stable performance over long periods of time and across a wide range of operating temperatures.
The Gallios houses up to three solid-state lasers in standard red and blue, with violet available as an option.
Interchangeable optical filters facilitate detection of a variety of dyes and wavelengths.
A forward-scatter detector provides up to three measurements of cell size and visualisation of particles down to 0.404mm in diameter.
A side-scatter detector incorporates an independently focused, high-performance photodiode with electronic attenuation.
Six fluorescence detectors provide simultaneous acquisition of up to six fluorescence signals.
Up to four fluorescence detectors can be added to the system, enabling concurrent reading of up to 10 colours.
Simultaneous measurements of integral, peak and width are available for all parameters, including scatter and fluorescence signals.
A selection of up to 62 parameters can be processed per analysis, at acquisition rates of 25,000 events-per-second, with high yield.
Three scalable configurations allow for the future addition of more lasers and fluorescence detectors as the applications for complex multi-colour flow cytometry expand.
Beckman Coulter is also launching a web portal to support cytometry research.
Features of this resource include a variety of specially designed interactive tools, such as cell signalling maps, a fluorochrome spectral overlap viewer and an experimental design tool to help cytometrists set up applications.
Users will be able to access the latest flow cytometry product information, view extensive reference resources and order reagents.