Millipore Corporation has announced its single-use Chromasorb membrane adsorber.
Chromasorb devices bind negative impurities from host cell protein (HCP), DNA, endotoxins and viruses at salt concentrations well above those of traditional resins and membranes.
The technology behind the Chromasorb solution enables these devices to function at a wide range of salt concentrations, eliminating the need to dilute feedstreams prior to processing.
This ability avoids the downstream bottleneck of buffer tank capacity that is inherent to competitive disposable adsorbers at the polishing step.
The Chromasorb solution is comprised of a linearly scalable range of devices.
The Chromasorb 0.08mL process development device requires one-third less volume of feedstock than other membrane adsorbers, allowing for the design of robust experiments.
Chromasorb 0.08mL devices for process development, optimisation and scale up are currently available.
Chromasorb 50mL and 500mL devices will be available soon.
