Pall is to showcase its biotechnology offerings, including Stax single-use systems and filtration technologies, at Achema 2009.
The Pall Stax single-use depth filter platform helps reduce utility expense and labour time associated with the production of biopharmaceuticals, and is a flexible system for pre-filtration and clarification processes.
It also eliminates cleaning validation requirements incurred by manufacturers with traditional plate and frame depth filtration systems.
The platform can be anchored to the floor or placed on casters for easy mobility, and its compact vertical design (up to 6ft/2m high) is scalable for size and performance to meet laboratory, pilot and process needs.
The Pall Stax system features interchangeable, single-use depth filter capsules housed in a stainless-steel chassis that can be managed by one operator.
The capsule sizes (small, medium and large) allow mix-and-match increases in filter area throughout the system's modular design.
The platform uses Pall's cellulose-based Seitz high-performance depth filter media and its second-generation Supradisc II dual drainage plate modular design to encapsulate the media, ensuring high-performance filtration and overall process stability.
Pall's Supracap 60 and 100 capsule filters complement the Stax system and allow process development from early research and development to full-scale manufacturing with a highly predictable scale-up range of single-use capsules.
Pall will also display a range of biotechnology and biopharmaceutical offerings from laboratory to process scale.
Pall Allegro 1,000-litre 3D biocontainers complement the 100, 200 and 500-litre sizes introduced last year and deliver a scalable product line that enhances the performance of Pall's single-use systems for large-scale biotechnology and pharmaceutical manufacturing applications.
Pall Q and S Hypercel ion exchange sorbents are advanced chromatography sorbents for processing large amounts of protein during the capture and intermediate steps of purification.
Pallsep Biotech PS50 oscillating membrane filter system is for biotech applications requiring advanced tangential flow filtration for processing viscous or high-solids materials.
Pall Fluorodyne EX grade EDT filter is a 0.1 micron sterilising grade filter designed for high-throughput culture media applications that require secure mycoplasma control.
In addition to these technologies, Pall is highlighting five initiatives that address current industry challenges, including: flexible solutions that feature Allegro single-use systems; process economics that address enhanced chromatography components and systems; high-performance filtration providing single-use pilot- to production-scale clarification; total contamination control - the removal of the spectrum of potential risk organisms such as viruses, mycoplasmas, host cell proteins, DNA and bacteria; tangential flow filtration (TFF) systems and T-series cassettes that improve concentration and diafiltration of proteins and other molecules.
