MWG Biotech AG and Eurofins Medigenomix have upgraded their Genome Sequencer (GS) 20 from Roche to the next-generation Genome Sequencer FLX system.
The companies' sequencing platform is based on the combination of Sanger sequencing and sequencing-by-synthesis technology, supported by customised bioinformatics, which allows them to sequence and compare bacterial genomes in a couple of days.
Although the GS 20 system delivers 200.000 sequence reads with an average read length of 100 - 120 base pairs in a single run, the next generation GS FLX system increases the throughput fivefold.
It allows the two companies to sequence 400.000 reads with an average read length of 220 - 250 base pairs, generating 100-million base-pairs in only 7.5 hours and with higher accuracy per individual read and at the consensus level.
