Amsbio has announced a number of new kits for proteoglycan research.
A sandwich Elisa kit for measurement of keratan sulphate (KS) is now available.
The kit offers 10 times the sensitivity of previous Elisa kits (down to 0.25ng/ml) enabling measurement of KS in various animal samples, including serum and synovial fluid, where KS is present only at trace levels.
Hyaluronic acid (Hyaluronan) is a glycosaminoglycan polymer critical for maintaining the cellular integrity of the extracellular matrix and in its lower molecular weight form participating in many biological processes.
Based upon a competitive protein-binding inhibition method, a new assay kit from Amsbio offers sensitive and highly specific measurement of hyaluronic acid in body fluids, culture medium, and tissue extracts.
Heparan sulphate proteoglycans (HSPG) are known to play important structural and functional roles in linking the component proteins of the basement membrane, controlling the permeability properties of the membranes and signal transduction.
To date, a handicap in HSPG research has been a lack of a sensitive and more importantly specific test for human heparanase activity.
Furthermore HSPG research has also suffered from a lack of a purified enzyme or instability of the cloned enzyme limits assay design.
To address these shortfalls - Amsbio has launched two new non-radioactive assay kits that offer sensitive and specific quantitative detection of heparanase in cell culture supernatants, human plasma, biological fluids and tissue samples.
Supplied in a 96-well plate format, the kits are fast and easy to use.
Amsbio offers a range of products for glycobiology research including carbohydrates, enzymes, antibodies and assay kits.