GE Healthcare has announced the launch of Biacore X100 2.0 and Biacore X100 Plus Package 2.0, adding functionalities to the automated real-time molecular interaction analysis system.
Single-cycle kinetics is now the preferred method for kinetic analysis with Biacore X100 2.0, which also includes specifications for detection of small molecules (as low as 100 Da), and pre-programmed assay workflows for all Biacore Capture kits, including the recently launched Biotin Capture kit.
Single-cycle kinetics enables kinetic analysis without the need for sensor surface regeneration, reducing time taken to develop and run an assay and allowing analyses that would otherwise not be feasible due to difficulty in finding suitable regeneration conditions.
The Biacore X100 Plus Package 2.0 features calibration-free concentration analysis (CFCA), and software support for the special considerations required in analysis of small molecules requiring DMSO for solubility.
CFCA is a methodology unique to Biacore T100 and Biacore X100, for determining concentration related to specific binding activity without the need for a standard.
Using CFCA can reduce error and improve accuracy in affinity and kinetics measurement.
