CLC Bio has released the beta version of its assembly algorithm for de novo assembly.
The new assembler comes in two different editions, as a standalone command-line interface and as a graphical user-interface through a plug-in for CLC Genomics Workbench.
Soren Monsted, user-experience manager at CLC Bio, said: 'There are two major features that set our de novo assembler apart from other de novo assembly tools in the market.
'The first is the memory requirements, which are far less than required by other solutions in the market, making assembly of the human genome possible on a single computer with 32GB of RAM.
'The other major feature is the speed where the aforementioned 32GB RAM computer can de novo assemble a 37-fold coverage human genome in around seven hours,' he added.
Eva Stukenbrock, who is carrying out post-doctoral research at Bioinformatics Research Center (BiRC) at the Aarhus University, is comparing genomes of disease-causing fungi in order to reveal patterns of evolution and host specialisation.
She has used CLC Genomics Workbench for both reference assemblies of Illumina reads and genome analyses and is now also applying the de novo assembler to her large genome dataset.
The de novo assembler beta version supports data from multiple high-throughput sequencing instruments, including hybrid de novo assemblies with Illumina, Roche 454 and Sanger data.
The aim is to release the final version in the first quarter of 2010.
