Copley Scientific has announced it will introduce the Dusa shaker, a new automation device for inhaled product testing, at RDD 2010.
This small-footprint unit automates the rinsing of Dusa collection tubes, increasing productivity and enhancing the reproducibility of drug recovery, especially for low-solubility formulations.
It also reduces the risk of operator exposure to repetitive-strain injury.
Dose uniformity testing is mandatory for all inhaled products to confirm consistency from batch to batch and across the product lifetime.
Individual shots are recovered from a Dusa collection tube by thorough rinsing and post-testing with an appropriate solvent.
This manually intensive agitation process is prone to inter- and intra-operator variability and any failure to adequately wet all internal walls compromises drug recovery and the integrity of the results.
The Dusa shaker holds up to 21 MDI or 12 DPI collection tubes on a series of rollers, subjecting them to a controlled lateral shake and rolling action; shaking frequency and duration can both be set according to test requirements.
This process ensures that all internal surfaces are adequately wetted and that agitation is performed with a smooth yet vigorous action.
The unit can be supplied with supporting IQ/OQ documentation.
It has a footprint of just 570 x 610mm, making it ideal for the laboratory bench.
