Biotage has announced the addition of Evolute WCX to its family of tools and technology for medicinal and analytical chemistry.
Evolute WCX is a mixed-mode weak cation exchanger, developed for extraction of strongly basic analytes and quaternary amines from aqueous samples.
These analytes are typically found in pesticides and provide analytical scientists with the ability to extract pesticides from diverse matrices, ranging from ground water to blood samples.
The resin-based sorbent is surface modified with well-defined hydroxyl-functional oligomers.
An optimised combination of non-polar (hydrophobic), polar (hydrophilic) and cation exchange interactions allows efficient extraction of strongly basic analytes of wide ranging polarities and quaternary amines, allowing for up to 50 per cent more efficient recoveries of pesticide residues.
The non-polar/cation exchange dual retention mechanism allows the use of a rigorous interference regime, providing clean extracts and reducing matrix effects associated with LC-MS/MS analysis.