Thermo Fisher Scientific has unveiled its Thermo Scientific TSQ Quantum XLS at Pittcon 2010.
The triple quadrupole gas chromatography mass spectrometry (GC-MS) system is designed to offer maximum precision, sensitivity and laboratory productivity for quantitative GC-MS analysis.
It features the Thermo Scientific Durabrite Iris ion source, which is claimed to ensure high sensitivity in the low femtogram range, higher quantitative precision at trace levels and uninterrupted operation for increased productivity.
Equipped with optional column backflush solutions, the TSQ Quantum XLS enables high-throughput laboratories to run increased Quechers extract samples for 24/7 routine operation.
Highly inert and exchangeable ion volumes allow for quick preventive maintenance within minutes without venting the vacuum system.
The system is suitable for trace residue laboratories in food safety and environmental, forensics, toxicology and petrochemical laboratories.
The TSQ Quantum XLS provides low femtogram sensitivity for the most challenging trace analyses such as pesticides, PCBs, dioxins, PAHs, drugs and steroids in complex matrices.
It is designed to improve laboratory efficiency and throughput by identifying and analysing a very large number of compounds in a single analytical run.
The robust design of the Durabrite Iris high-sensitivity ion source delivers ion source inertness against the decomposition of labile compounds and provides higher ionisation efficiency for low fg detection.
The high-precision hyperbolic quadrupole rod analyser allows for analytical flexibility, high-speed data acquisition and more sample runs.
The 90deg collision cell virtually eliminates neutral noise background in the chromatogram for amplified analysis of complex samples.
All target compounds on the TSQ Quantum XLS are individually monitored at the compound retention time by using the timed-SRM acquisition.
Up to 3,000 selected reaction monitoring (SRM) scans can be time programmed in one chromatogram for the screening and precise quantitation of several hundred compounds at optimum dwell times in a single analysis.
The increased mass resolution possible with the highly selective reaction monitoring (H-SRM) capability of the system enables correct peak area integration for higher quantitative precision, delivers lower LOQs and eliminates false positive results.
When operated in multiple reaction monitoring (MRM) mode, the TSQ Quantum XLS delivers low femtogram detection for multi-class multi-residue target compound analysis in complex matrices.
This level of sensitivity and selectivity, combined with quantitation-enhanced data-dependent MS/MS (QED-MS/MS), which provides simultaneous quantitation and structural confirmation, is designed to increase laboratory productivity.
The TSQ Quantum XLS can be configured as a fully equipped pesticides analyser for quick method setup in routine laboratories.
The pesticide analyser configuration is accompanied by the Pesticides Method Reference manual, with more than 600 pesticide compounds listed for immediate MRM analysis.
The Quechers sample preparation method and a full GC-MS/MS setup procedure is delivered on CD for quick startup into production.
Increased robustness with short analytical cycles is achieved by the proven backflush solution, keeping the injector and column free from high boiling matrix compounds, otherwise requiring extended run times for bake-out and cleaning.
Only the analytes of interest enter the analytical column, while a pre-column and injector is backflushed during the regular analysis run being cleaned for the next injection, ensuring shorter cycle times between sample injections.
The instrument utilises the latest version of Thermo Scientific Quanlab Forms chromatography analysis software package.
Quanlab Forms 3.0 is a layered application software solution that is designed to offer improved acquisition, review and reporting features for increased productivity.
The software features dual-reagent gas selection and plumbing capabilities to deliver stable and reproducible results.
The TSQ Quantum XLS is also compatible with the Envirolab Forms 3.0 and Toxlab Forms 3.0 software platforms.