Genetix has enhanced its Cellreporter system, developed for the quantification of cellular responses.
The system offers a multi-application platform that is suitable for a range of cell-based assays, such as cell-cycle analysis, cytotoxicity studies and monitoring protein translocation.
These assays are used as biological models of physiological situations, for example when investigating the effect of drug candidates on a cancer-cell model.
Using the Cellreporter system enables scientists to increase throughput of these assays without compromising image or data quality.
In addition, the accuracy of the quantitative data can be substantially improved compared to conventional approaches.
Flexible image analysis software identifies and analyses each object, such as the cell nucleus, thereby distinguishing between the responses of individual cells within heterogeneous populations.
Users can optimise and standardise image interpretation for each assay, view cell morphology and check data quality - for example to remove fluorescent debris that may compromise results.