Biofocus has launched four biologically targeted libraries, containing novel, drug-like compounds that specifically target kinases and protein-protein interactions.
The three new Softfocus kinase libraries (SFK61, SFK62 and SFK63) target either the hinge region, allosteric sites or novel binding modes.
The SFK collection has been independently determined to have the greatest population of kinase-like molecules available for screening, according to Biofocus.
The company's second Helix Mimetic library (HM02) is based on a novel structure that interacts with protein helices.
This library is designed to inhibit protein-protein interactions but can also target other helical recognition motifs, such as the pore region of ion channels.