Biotage has been awarded US patent 7686959: Control System and Method for Flash Separation.
This technology converts thin-layer chromatography (TLC) compound retention data into a linear gradient and also provides the user with sample loading estimates for any Biotage flash cartridge.
The TLC-to-Gradient technology removes all of the trial and error associated with developing flash purification methods.
Biotage recently launched related gradient technology for its Isolera flash purification product line.
The enhanced gradient optimisation (GO) technology is said to reduce solvent use and cost by 60 per cent or more.
With GO technology, results from linear gradients can be purified at a larger scale with an optimised step gradient, which reduces solvent use by as much as 60 per cent.
The GO solvent-saving feature is available on all new Isolera systems.
