Amsbio has launched a range of recombinant proteins for cell-culture and tissue-engineering applications that can substitute extracellular matrix proteins currently extracted from mouse sarcoma.
The Mussel Adhesive Protein-based matrix (Maptrix) ECM line of products are coating reagents with genetically incorporated bioactive peptides, which mimic the extracellular matrix (ECM) activity of collagen, fibronectin, laminin and vitronectin proteins.
These bioactive peptides mimic ECM proteins and provide for cell attachment, spreading and growth.
A Maptrix surface coating offers an animal-free, chemically defined attachment and growth surface that provides a highly controlled environment for cell culture and tissue-engineering applications.
The Maptrix ECM line of products provide an alternative to the conventional chemistry approach.
In addition to RGD motifs, Maptrix includes a variety of alternative motifs that mimic the extracellular matrix (ECM) activity of collagens, fibronectin, laminin, vitronectin and other matrix proteins.
The Maptrix ECM line of flexible products can be used in cell-culture applications alone, or in combination with other products.
All Maptrix products are soluble in a variety of buffers, including water of pH2 to 9.5.
Available for basic research or drug-discovery applications in serum-free or serum-reduced conditions, Maptrix products are provided as ready-to-use aqueous-coating formulations in 1, 2.5, 5 and 10mg sizes (vials).
