Hamilton has added online pH monitoring to its Biolevitator 3D cell culture system for researchers in drug discovery and development, therapeutics and regenerative medicine.
The integrated pH reader monitors the quality of the cell culture media with non-invasive optical measurement, notifying the user when the pH drops below a defined level.
This precise monitoring enables media changes only when needed, rather than on an arbitrary schedule.
This minimises cell culture interruptions and optimises consumption of media, Hamilton said.
Two pH monitoring modes can be enabled: qualitative colour, which reports absorbance at 560nm, and semi-quantitative, in which the pH value is calculated using several parameters and inputs.
Both absorbance and pH decrease while cells are growing.
The pH meter is an optional addition to the Biolevitator, which also includes temperature and CO2 control.
The Biolevitator, developed in collaboration with Global Cell Solutions, is an automated bench-top 3D cell culture system that delivers productivity gains to researchers in drug discovery and development, therapeutics and regenerative medicine.
The Biolevitator uses Global Cell Solutions' Global Eukaryotic Microcarrier and can grow four independent, high-density cell cultures at once while eliminating the need for peripheral instruments such as incubators and centrifuges.
