The E-Plate View 96 from Roche combines the possibility to perform label-free real-time monitoring of cells and visual inspection in one device.
E-Plate View 96, a modified version of the E-Plate 96, is a single-use, disposable device used for performing cell analysis assays on the Real-Time Cell Analyzer (RTCA) Single Plate (SP) and Multiple Plate (MP) Instruments.
It enable downstream or intermediate visual inspection of cells using microscopes and automated cell imaging systems such as Roche's Cellavista Instrument.
Precise, quantitative information is provided during all phases of comprehensive experiments about the status of cells, including cell number, cell adhesion, cell viability and cell morphology.
A label or fixation of cells is not needed.
For the modification, four rows of microelectrode sensors were removed in each well to form a window for visual inspection.
The gold electrode covers approximately 70 per cent of the bottom area.
The E-Plate View 96 has identical outer dimensions as the E-Plate 96 and enables users to work with both plates in parallel in RTCA SP and MP Instruments without adapters.
According to Stoffel, the E-Plate formate will find its use mainly in cancer research, basic research (developmental biology, receptor biology and embryology), dermatology and neurobiology.
