Beckman Coulter is exhibiting a portfolio of laboratory equipment for biotherapeutic formulation scientists at this year's Pharmaceutical Sciences World Congress.
Instruments in the suite can be used for characterising protein charge, analysing individual protein molecules, studying formation of dimers and trimers and for quantifying large aggregates in applications from basic biochemical discovery through large-scale production.
A capillary electrophoresis system, micro-ultracentrifuge and particle-size analysers will be available for viewing in booth 346, along with systems experts who can answer questions and offer advice regarding specific applications.
Featured technologies will include the PA 800 Plus pharmaceutical analysis system, a next-generation CE platform that integrates quantitative, qualitative and automated solutions for analysis of protein purity, charge isoform distribution and glycan heterogeneity.
The Optima Max-XP Micro-Ultracentrifuge, which is suitable for protein formulation applications, will also be on display.
This centrifuge can produce sedimentation forces greater than 1,000,000g, features a customisable user interface and incorporates a number of enhanced biosafety attributes.
Quantifying aggregates between one and 10 microns is useful in protein formulation and Beckman Coulter's aggregate counting solution, the Multisizer 4, will feature a sample holder that enables working with volumes as small as 4ml.
The Delsanano, Beckman Coulter's dynamic light scattering and zeta potential solution, will also be shown.
This system can be used for sizing proteins in solution and then studying their stability.
Completing the particle characterisation offerings, the LS 13 320 laser-diffraction system can size therapeutics ranging from 0.017 to 2,000 microns in dry powders, aqueous suspensions or solvents.
Staff will be available to discuss the Proteomelab XL-I protein characterisation system, which, although not being exhibited, may be of interest to protein chemists.
This analytical centrifuge provides large quantities of information about protein formulations by sequentially collecting data from an on-board scanning UV/Vis detection system and Rayleigh Interference Optics.
The Pharmaceutical Sciences World Congress takes place from 14-18 November at the Morial Convention Center in New Orleans.
