Thermo Fisher Scientific has developed a fast screening method enabling labs to simultaneously screen and confirm the presence of more than 1,000 pesticides at low levels using a single injection.
Other commonly used techniques require multiple injections in order to comply with increasingly stringent regulations.
Through using the Thermo Scientific Quantum GC, this method can acquire 3,000 timed selective reaction monitoring (SRM) transitions per run, increasing sample throughput while ensuring accuracy in a matrix.
Pesticides used to prevent, destroy and control pests on food crops often leave residues on agricultural products that are said to pose risks to consumers.
According to Thermo Fisher Scientific, effects range from short-term health problems such as headaches and dizziness to long-term damage to the nervous system and in some cases, cancer.
Gas chromatography (GC) with element-selective detectors and single quadrupole gas chromatography/mass spectrometry (GC/MS) are techniques commonly used for GC-amenable pesticide residue analysis in laboratories.
As the use of pesticides increases and maximum residue levels (MRLs) set by regulations become more stringent, labs are requiring alternatives to existing techniques that require one sample be analysed using several injections and multiple methods.
Thermo Fisher Scientific's GC-MS/MS method enables the rapid screening and confirmation of more than 1,000 pesticides in just one injection, increasing productivity and delivering results faster.
The method is designed to facilitate compliance with the European Council Directive 96/23/EC, which requires at least two SRM transitions per compound.
In this method, scientists analysed 303 pesticides in green beans in a single run using the TSQ Quantum GC under timed-SRM mode.
The timed-SRM function enabled the acquisition of a total of 652 transitions.
The dwell time of each transition was automatically maximised for each compound to give the best sensitivity for all pesticides.
Using this method, linearity and recoveries are achieved within industry requirements and sensitivity can easily reach 0.0040mg/kg for all pesticides in green beans.
The new method demonstrates that timed-SRM mode is an extremely effective method for screening and determining large amounts of pesticides at low levels in the sample matrix.
