Trevigen has released control cells and buffer system for the standardisation of comet assays run under neutral conditions.
The neutral comet assay aids in the discrimination between single-strand and double-strand breaks in DNA, which is a useful tool in drug discovery.
Trevigen's Neutral Cometassay control cells are a set of cell preparations containing different levels of DNA damage to be used as controls with Trevigen's Cometassay kits.
When performing the Neutral Cometassay, the four control cell populations show incremental increases in tail movement.
Additionally, Trevigen has identified a new buffer system that enables easy discrimination between the comet head and tail in the Neutral Cometassay.
The combination of cryopreserved control cells and reformulated buffer system is designed to standardise and compare comet assay results under neutral electrophoresis conditions between individual users and laboratories.
