Germany-based Orgentec Diagnostika has developed Liver-9-Line, an immunoblot test for the serological diagnosis of autoimmune hepatitis (type 1 and type 2 AIH) and primary biliary cirrhosis (PBC).
The test system also allows for the reliable differentiation of these autoimmune diseases from other diseases of the liver.
This immunoblot is suitable for initial and differential diagnosis in cases of ambiguous symptomatology or for differentiation of a positive result from screening carried out with ELISA or immunofluorescence tests.
Orgentic claims that the antigen set included in this immunoblot is unique on the market, because, in addition to the three ASMAs, F-actin, myosin, and desmin, Liver-9-Line also detects antibodies against soluble liver antigen (SLA/LP), liver kidney microsomal type 1 (LKM-1) and liver cytosol antigen type 1 (LC1).
The PBC-typical autoantibodies detected by this immunoblot include AMA-M2, as well as antibodies against Sp100 and gp210.
Orgentic's analytical software allows for the automated evaluation of the immunoblots.
Ivision Scanware is designed to objectively analyse and securely archive test data.
Liver-9-Line is available in packages of 8 or 16 immunoblot strips and all reagents are ready for immediate use.
Each individual blot strip includes serum, conjugate control and cut-off control, as well as an individual code that eliminates accidental mix ups.
