TAP Biosystems has announced the first installation of its micro bioreactor system (AMBR) with integrated cell viability analyser for a pharmaceutical company.
This walk-away system will be used to assist in predicting how antibody-expressing cell lines will perform in large-scale bioreactors.
TAP Biosystems' specialists integrated the customer's Cedex Hires cell analyser into the system's workflow.
The ability to manage its AMBR system with cell counting from one central point is enabling the pharma company's researchers to reproducibly control and evaluate the behaviour of their antibody-expressing cell lines at micro scale (10-15ml working volume).
Unattended cell counts can be performed outside of normal working hours, supporting experiments overnight or at weekends.
Using the AMBR software, scientists at the pharmaceutical firm can control culture conditions, initiate online measurement of cell number and viability, and collect cell-analysis data.
They can also set up the AMBR to make automatic feeds based on the integrated cell-count data, providing a truly walk-away automated bioreactor system.