Researchers are attempting to make electricity from electrodes coated in bacteria and using light or hydrogen as the fuel.
The aim of the research is to develop more efficient biofuel cells, seen as the future of electronics.
Most biofuel cells create electricity using enzymes that process glucose, but the Leeds research will focus on bacterial enzymes that can harness light or hydrogen gas to create energy. The work is funded by a £1.42m grant from the European Research Council.
Lead researcher, Dr Lars Jeuken, from the University’s Faculty of Biological Sciences, said: “Technology that creates an electrical signal from a biochemical reaction is already in commercial use, for example in blood glucose biosensors.
“However, developing an efficient biofuel cell that can create sufficient electricity for general use has proved much more difficult. This is mainly because the systems developed to date have only limited control of how inorganic materials and biological molecules interact.
In their simplest form, biofuel cells have two electrodes, one which removes electrons from a fuel - for instance glucose or hydrogen - while the other donates electrons to molecules of oxygen, making water. When these are connected by a wire, they form a circuit, resulting in an electrical current.
This new project will begin by applying this technique to two specific groups of enzymes, one which harnesses light and the other, hydrogen.
These are found in membranes of chloroplast - the parts of cells which conduct photosynthesis - or bacterial cells, both of which have promising applications in biofuel cells.
The final part of the project will aim to connect electrodes to the membranes of living bacterial cells.
“Not only will this help scientists understand the role of different enzymes in making energy, but how best to capture and use this energy in electrical applications,” says Dr Jeuken.
Dr Jeuken’s research will also contribute to a new Interdisciplinary Centre for Microbial Fuel Cells (ICMFC), set up jointly between the Universities of Leeds, Sheffield and York.