The Trilencer-27 siRNA claims to provide improvements over the use of traditional 21mer siRNA designs.
Gene silencing through the use of RNAi has become a primary tool for characterising gene involvement in disease states and interactive pathways.
Offering genome-wide coverage against human, mouse and rat, the AMSBIO Trilencer-27 siRNA kit takes advantage of the natural processing by Dicer to produce 10-fold higher potency and specificity than shorter 21mer RNAi forms.
The 27mer dicer-substrate duplexes in the kit also evade the radar of the mammalian interferon response when expressed in mammalian cells and initiate strong and specific gene silencing.
Through its design (3 gene specific siRNAs and 1 negative control) - Trilencer-27 siRNA delivers the dual advantages of improved efficacy (>70% gene knockdown) and minimal interferon response.
