Porvair Sciences has published a brochure providing background to Chromatin Immunoprecipitation (ChIP) and introduction to Chromatrap ChIP assay technology.
Chromatrap, the novel solid-based matrix for ChIP assays available from Porvair Sciences, has been successfully used to isolate high quality chromatin from a wide range of biological matrices by research groups around the world.
It uses a solid phase porous polymer functionalised with either protein A or G, allowing the chromatin capture to be more sensitive and efficient than bead based methods.
The Chromatrap spin column approach offers advantages including shortened protocol length (ChIP in under 5 h), less manual handling and sampling loss when compared to other methods based on sepharose or magnetic beads.
Two formats are available, single spin column and 96 well microplate high throughput devices, both with high quality DNA enrichment for samples between 50ng-7000ng.
For a copy of the new brochure ‘A more efficient, sensitive and robust method of chromatin immunoprecipitation’ visit the downloads section of www.chromatrap.com or contact Porvair Sciences on +44 (0)1978 666239 or int.sales@porvairsciences.com
