Porvair Sciences has joined forces with researchers at Swansea University to write a technical article entitled ’Chromatrap 96: a new solid-state platform for high-throughput Chromatin Immunoprecipitation (ChIP)’.
Epigenetics is a fast-growing research area with wide applications, including disease mechanism profiling and personalised medicine strategies. ChIP is crucial to epigenetic research.
Published in the latest issue of Nature Methods (11, 2014), the article provides an introduction to Chromatrap 96 - a high-throughput ChIP analysis platform. It demonstrates how the platform can profile up to 96 transcription factors and epigenetic modifications simultaneously in less than one day.
The authors of the article have aimed to show how Chromatrop 96 enables sensitive, selective and reproducible target amplification with excellent signal-to-noise ratios, even from samples as small as 0.1 µg.
The compatibility of the platform with automated handling also allows for simultaneous investigation of parallel epigenetic landscapes, offering unprecedented ChIP assay flexibility and speed.
