Chromatrap, a Porvair Sciences product, has launched its own range of Chromatin Immunoprecipitation (ChIP)-validated antibodies.
Building on the company’s success in the solid-state ChIP market the addition of ChIP-validated antibodies is designed to further enhance Chromatrap’s high performance application solutions.
Product development manager Amy Beynon said: “The use of high quality and specific ChIP-validated antibodies is essential for the success of a ChIP assay. The antibody must recognise and bind to native protein that is bound to DNA. Antibodies from other applications do not always work well in ChIP. That is why our team has thoroughly investigated the top ten most referenced antibodies in recent epigenetic research papers.
“We are pleased to be able to offer these top quality validated antibodies to our customers alongside our expanding range of kits for ChIP assays of every type. This will give our customers confidence in their protocols and their results, safe in the knowledge that a ChIP-validated antibody was at the heart of their assay.”
The first nine antibodies in Chromatrap’s Validated Antibody programme are H3, RNA pol II (S), RNA pol II (S5), H3K9me3, 5mC, AcH3, AcH4, AR and Sin3a.
“It is our intention to expand the range as we continue to identify, source and validate antibodies for ChIP experimental use. We hope to have most of the major epigenetic marks validated over the next 12 months,” Beynon said.
Chromatrap-validated antibodies are available in 100uL aliquots at a concentration of 1mg/ml, delivered overnight from the company’s Wrexham, UK facility to customers worldwide.
