New mass spectrometry instruments and proteomics software to improve the identification and quantification of chemicals and biological molecules in many applications
Agilent Technologies has announced the expansion of its mass spectrometry (MS) product line with five new products, including Agilent's first Tof mass spectrometer, improved quadrupole models, and a powerful new high-throughput proteomics software package.
These new products improve the identification and quantification of chemicals and biological molecules in applications including environmental screening, drug discovery and development, and proteomics.
"Mass spectrometry is essential for a wide range of chemical analysis disciplines and expanding life science research fields," said Chris van Ingen, senior vice president and general manager of Agilent's life science and chemical analysis business. "The introduction of our Tof instrument is a significant milestone in the expansion of our mass spectrometry-based solutions and provides a complement to our quadrupole and ion trap systems.
Agilent is committed to improving our new and existing solutions for customers." The five new products introduced include the following.
Agilent LC/MSD Tof (time-of-flight) mass spectrometer.
The Agilent LC/MSD Tof is uniquely designed to provide leading-edge mass accuracy while reducing the complexity of instrument use.
With 3ppm mass accuracy, low-femtomole sensitivity, and 10,000 resolving power, the Agilent LC/MSD Tof offers chemists who synthesise drug candidates definitive molecular weight and elemental composition information.
This provides the extra confidence required for publication or patent application.
The LC/MSD Tof is expected to be available for order on 1 August.
Agilent 1100 series LC/MSD ion trap mass spectrometer.
The Agilent 1100 series LC/MSD trap family of ion trap mass spectrometers are the most versatile mass spectrometers offered by Agilent.
These products are used for a wide range of applications including detection of trace-level environmental toxins and identification of low-abundance proteins.
The new LC/MSD trap XCT features a new, high-capacity ion trap and related changes, yielding a ten-fold increase in sensitivity and significant improvements in scan speed and/or mass resolution over Agilent's current ion traps.
The LC/MSD trap XCT's new peptide scan mode improves identification of proteins from complex peptide digest mixtures.
The Agilent 1100 series LC/MSD trap XCT is available now.
Spectrum Mill MS proteomics workbench Mass spectrometry is a core technology for proteomics research, but large-scale proteomic research can generate enormous volumes of MS data.
The lack of high-throughput data analysis software has presented a significant bottleneck in the workflow of MS researchers.
Agilent's new Spectrum Mill MS proteomics workbench is a suite of software tools for processing MS and MS/MS spectral data, determining protein identities and expression levels, and creating meaningful cross-sample and cross-experiment results summaries.
The product features intelligent extraction and quality assessment of the raw spectral data, and intelligent parallel processing during database searching, allowing the Spectrum Mill workbench to process data in minutes as opposed to the hours or days required using other approaches.
The Agilent Spectrum Mill MS proteomics workbench is available now.
Agilent orthogonal nanospray ion source.
Available for the LC/MSD trap XCT and the other Agilent ion trap mass spectrometers is a new orthogonal nanospray ion source.
This product operates at the nanolitre-per-minute flow rates that provide the utmost in electrospray sensitivity.
This is the only nanospray ion source available that uses Agilent's patented orthogonal spray technology to minimise required adjustments and maximise reliability.
The orthogonal nanospray ion source, LC/MSD trap XCT, and Spectrum Mill workbench together form a powerful solution for identification of low-abundance, biologically significant proteins.
The orthogonal nanospray ion source is available now.
Agilent 1100 series LC/MSD VL and SL quadrupole mass spectrometers.
Upgraded models of the Agilent 1100 series LC/MSD VL and SL quadrupole mass spectrometers provide significant improvements in performance. Each use a single, split-flow turbomolecular high-vacuum pump that improves pumping capacity.
With fewer components and moving parts, this simplified vacuum system should further boost the LC/MSDs' outstanding reliability.
Also new are enhanced ion optics.
Combined with the improved pumping in the ion optics region, the enhanced ion optics give the LC/MSD an approximately 2X improvement in sensitivity.
The updated Agilent 1100 series LC/MSD VL and SL models are expected to be available in July.
