A comprehensive range of automated protein characterisation solutions including molecular weight determination, peptide mapping, isoelectric focusing, and carbohydrate profiling
Beckman Coulter introduces the ProteomeLab PA-800 protein characterisation system for the automated, high-resolution analysis of proteins.
Part of the company's new ProteomeLab family of products, the PA-800 offers a comprehensive range of automated protein characterisation solutions including molecular weight determination, peptide mapping, isoelectric focusing, carbohydrate profiling and mechanisms to study protein/protein interactions in solution.
Based on Beckman Coulter's well-established automation and capillary electrophoresis technologies, the PA-800 addresses important issues in the characterisation of a given proteome - manipulating and resolving low levels of proteins that range from acidic to basic to membrane-bound.
The PA-800 includes specialised chemistry, software, training and support.
The system works with the ProteomeLab PF 2D, a new two-dimensional protein fractionation system that resolves thousands of proteins in liquid phase. "Protein differences between normal and diseased tissue are resolved and fractionated into a 96-well plate using the ProteomeLab PF 2D system," explains Chapman.
"Wells containing unique fractions are highlighted by the system's differential display and may be easily transferred to the ProteomeLab PA-800 for extensive characterisation".
The PA-800 and PF 2D systems are further linked by Beckman Coulter's 32 Karat software, a central platform providing instrument control and data analysis for both systems.