Cellomics has announced that AstraZeneca is evaluating its CellSpace Knowledge Miner, a powerful new class of bioinformatics tools, in its pharmaceutical research programmes
"Cellomics is very proud to have a major international research-based pharmaceutical company such as AstraZeneca evaluate our technology," stated Ian Shaw, Cellomics's senior vice president of commercial development.
" We are proud to assist AstraZeneca in its commitment to the research and development of their high-quality pipeline of new products." CellSpace is a knowledge mining system that continuously monitors the research literature of molecular and cellular biology, automatically extracting and databasing information regarding relationships between molecules that are at the heart of biomedical research.
CellSpace computers continuously analyse the US National Library of Medicine's Medline database, performing proprietary statistical correlation analyses regarding the organisms, cell types, biological processes, and molecules reported on in biomedical research literature.
By using CellSpace, molecular biologists and drug discovery researchers are instantly able to access insights that previously required days or weeks of literature review.
With CellSpace, users can determine the biological functions most commonly shared by a cluster of gene products, which is useful for interpreting cDNA microarray data.
CellSpace can also determine which protein-protein interactions observed in a two-hybrid screen have not previously been reported in the literature, list all the molecular targets implicated in a disease, as well as the drugs known to act upon them, and more.
The answer a user receives is much more than a simple annotation retrieved from a curated database; rather, it is a consensus derived from more than one million research publications.
All answers are linked back to the reports from which they were derived, enabling the user to judge their accuracy.
New research literature is automatically analysed every two weeks, ensuring that CellSpace is always up-to-date. And, if an update occurs that is relevant to his query, the user can be notified via e-mail immediately.
