Can be used for qualitative differentiation between neuroendocrine and non-neuroendocrine neoplasms performed on either frozen or formalin-fixed paraffin embedded tissue sections
Cambridge BioScience has added rabbit anti-synaptophysin from Zymed Laboratories to its extensive range of antibodies.
Intended for in vitro diagnostic use, anti-synaptophysin can be used for qualitative differentiation between neuroendocrine and non-neuroendocrine neoplasms.
This is performed on either frozen or formalin-fixed paraffin embedded tissue sections using light microscopy.
Synaptophysin is a 38 kDa glycosylated peptide that was initially isolated from presynaptic vesicles of neurons.
It is the major transmembrane protein of synaptic vesicles and is ubiquitously expressed throughout the brain.
In a recent study, the synaptophysin antibody demonstrated immunoreactivity in 93% of neuroendocrine tumours demonstrating its usefulness in detecting neoplasia of neuronal and neuroepithelial differentiation.
These products are available from Cambridge BioScience in the UK and Ireland only.
