Using a proprietary treatment the hydrophobic/ oleophobic filters completely retain the acetonitrile/sample protein precipitation mix allowing complete mixing without loss or leakage
The new p3 from Porvair Sciences incorporates a novel dual filter design that eliminates the sample breakthrough and waste associated with leakages from traditional protein precipitation microplates.
The p3 allows 96 samples to be processed in one batch giving significantly improved productivity versus traditional methodologies.
The novel design of the p3 is readily integrated into automated systems offering the possibility of further throughput gains.
The protocol used by the plate is little changed from the familiar protein precipitation method. Using a proprietary treatment the hydrophobic/oleophobic filters in the p3 completely retain the acetonitrile/sample protein precipitation mix allowing complete mixing without loss or leakage.
The pre-filter in the new plate retains large flocculent particles avoiding problems due to 'plugging', while the final filter traps residual protein particles.
In addition the treatment has allowed a larger pore size than in traditional designs to be used resulting in an improved flow rate.
The inert nature of the filter materials ensures no adsorption of sample components.
For the first time, says Porvair, an optimised product is available that combines the productivity enhancing features of a 96-well microplate system with a proprietary design, avoiding the protein precipitation mess.
