Membrane adsorbers represent a special form of chromatography matrix, as they employ membranes with large pores rather than microporous particles
Based on the Sartorius technology platform, Vivascience has designed membrane adsorbers in spin columns specifically for protein research.
Membrane adsorbers represent a special form of chromatography matrix, as they employ membranes with large pores rather than microporous particles.
These pores span the entire filter area and enable a very rapid flow rate of the sample and an optimal binding of the target molecules within the easily accessible internal structure of the membrane.
Using these membranes for the construction of spin columns results in convenient devices for the selective separation of target proteins from complex solutions.
With the Vivapure acidic and basic protein purification kits, the first membranes with ion exchange chemistry in ready-to-use kits were successfully introduced into the market last year (2003).
In the meantime, the line of Vivapure membrane adsorbers was further extended with a number of new ligands.
Today, the following membrane adsorbers are available to the scientist: the Vivapure protein A spin columns to purify antibodies: the Vivapure epoxy protein coupling kit to arrive at tailor-made, highly selective affinity matrices; and the Vivapure metal chelate devices to purify established His-tag fusion proteins.
The Vivapure membrane adsorbers are also available for high-throughput applications in eight-strip and 96-well format.
