High-performance ion trap mass spectrometer has faster scan cycle time to improve peptide identification for proteomics research
Agilent has introduced a high-performance ion trap mass spectrometer (MS) that allows pharmaceutical and academic life-science researchers to identify 60 to 80% more peptides than preceding models in proteomics applications, such as protein identification and biomarker discovery, potentially leading to a better understanding of diseases like cancer and speeding drug development efforts.
The Agilent 1100 series LC/MSD Trap XCT Ultra offers significantly improved scan cycle times, enabling collection of mass spectra at rates up to three times faster than its predecessors.
"The combination of the new LC/MSD Trap XCT Ultra with Agilent's breakthrough HPLC-Chip/MS technology will set a new standard for protein identification and analytical performance," said Ken Imatani, product marketing manager for Agilent's ion trap mass spectrometers.
"The high resolution, scan speed and sensitivity of the LC/MSD Trap XCT Ultra make it a powerful tool for a wide range of qualitative applications in which high performance and productivity are essential, particularly in proteomics research".
"The LC/MSD Trap XCT Ultra is the latest example of Agilent's integrated approach to facilitating proteomics research, enabling researchers to solve their most challenging scientific questions more easily and with greater confidence," said Taia Ergueta, general manager of Agilent's proteomics and LC/MS business.
"The LC/MSD Trap XCT Ultra improves performance for a wide range of demanding applications in metabolite characterisation, natural products screening, product degradation studies and food and environmental analysis, which require excellent sensitivity and fast scanning capability".
The LC/MSD Trap XCT Ultra, which is based on an advanced multipole ion trap technology, has a full-scan MS/MS sensitivity specification of 250 femtograms for reserpine.
The system also has two new data-dependent neutral-loss analysis modes that provide enhanced data quality for analysis of phosphopeptides and glycopeptides.
The Agilent 1100 Series LC/MSD Trap XCT Ultra ion trap mass spectrometer (G4533AA) includes mass spectrometer, electrospray ionisation source, data system and LC/MSD Trap software (6.0).
It is expected to ship in July 2005.