Microwave enhanced peptide synthesis is 10-20 times faster than traditional methods and produces cleaner peptides with higher yields
CEM says its latest microwave-enhanced peptide synthesiser, the Liberty system, offers totally automated synthesis of up to 12 peptides in a day with the fastest cycle times and greater product purity than conventional synthesis.
Microwave enhanced peptide synthesis is 10-20 times faster than traditional methods and produces cleaner peptides with higher yields, it says.
"The introduction of microwave assisted peptide synthesis is the most important change in our chemistry in the last several years.
"It enables us to do even difficult sequences in high purity faster than ever before", said David Lofty, managing director of CEM Microwave Technology.
"Liberty brings the benefits of speed, increased yields and improved product purities to proteomics, opening up new possibilities in peptide synthesis".
Liberty's utilisation of microwave energy gives biochemists and other researchers the unprecedented ability to synthesise peptides that were previously inaccessible by conventional synthetic methods.
Liberty is available as a completely automated system with a scale range of 0.1 to 1mmol.
The system completely controls each reaction step in the process, using just moderate temperatures to shorten reaction times, with the microwave energy driving reaction steps so quickly that product racemisation is virtually eliminated.
Liberty is built on CEM's Discover platform and capitalises on the strengths of the base system, including CEM's patented focused technology and flexible software that enables chemists to change operating parameters quickly and run the unit from the onboard keypad or from a PC.