As interest in amyloid peptides continues to grow, AnaSpec has developed an extensive selection of catalogue amyloid peptides to match that interest
AnaSpec has been providing b-Amyloid peptides to leading Alzheimer's researchers for almost 10 years.
Equipped with expertise in both peptide synthesis and detection technologies, AnaSpec says it presents one of the world's most comprehensive collection of amyloid peptides.
Beta-Amyloid (AB) peptides, made up of long, insoluble ordered fibres, are glycoproteins deposited extracellularly in tissues in amyloidosis.
These peptides are generated as cleavage products from the membrane protein, Amyloid Precursor Protein (APP) by two proteases, b-secretase and g-secretase.
ABs are amphiphilic peptides with a hydrophilic N-terminal domain (residues 1 to 28) and a hydrophobic C-terminal (residues 29 to 40), the latter corresponding to a part of the transmembrane domain of APP.
These insoluble amyloid deposits found in Alzheimer's diseased brains have been the subject of increased interest for Alzheimer's treatment
