Chromatrap's solid state patented technology allows for ChIP-seq assays to be routinely performed from as little as 500ng of chromatin.
Availability of starting material has traditionally been a major problem for epigenetics researchers. The available techniques for tackling small samples which provide low yields of chromatin can be long and complex, and involve pooling or the spiking of samples with chromatin from another source.
Chromatrap ChIP-seq assay kits, which give a high signal-to-noise ratio, can achieve results with samples as small as 500ng and achieve high recovery of DNA for downstream applications such as next generation sequencing.
Utilising patented solid-state technology, the kit can deliver a streamlined ChIP-Seq protocol from tiny amounts of starting material and low chromatin concentrations. Specifically designed to work with broad chromatin concentrations, the latest ChIP-Seq kit combines the dynamic range of Chromatrap with the downstream analysis power of deep sequencing to enable faster, more reproducible genome wide identification of transcription factor binding sites and specific DNA associated protein modifications.