Shimadzu Scientific Instruments (SSI) has launched the PPSQ-51A single reactor and PPSQ-53A triple reactor gradient system protein sequencers, designed to offer users higher sensitivity and more reliable analysis of N-terminal amino acid sequences through automated Edman degradation.
The models can detect and identify additional rare and modified amino acids, as well as being FDA 21 CFR Part 11 compliant when used with SSI’s LabSolutions analysis data system.
PPSQ-51A/53A gradient system protein sequencers perform sequence analysis using gradient separation and a flow cell that enables high-sensitivity detection of PTH-amino acids. They are equipped with a high-performance detector and a solvent delivery pump for excellent pumping performance. With high retention time stability, operators can more confidently identify the correct amino acid.
PPSQ software enables simple operation, post-run processing, and reporting. Various functions allow the reprocessing of chromatograms, the overlaying of multiple chromatograms, chromatogram subtraction and automatic estimation of amino acid sequences. In addition, the PPSQ-51A/53A sequencers provide customised reports and yield graphs for a quick and comprehensive view of data. For regulated environments, using the PPSQ-51A/53A gradient systems with LabSolutions software enables compliance with FDA 21 CFR Part 11 guidelines for security, system policy, user management and audit trail requirements.
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