Peg-like spacer not only segregates the peptides from the reporter groups, but has better water solubility and ionisation ability, making it more amenable for mass spectrometry analysis
Fmoc-Ebes-OH (N-(Fmoc-8-amino-3,6-dioxa-octyl)succinamic acid) is an ideal spacer for peptide labeling in solid phase synthesis.
With its linear, flexible, hydrophilic structure, and well-defined molecular mass, this Peg-like spacer not only segregates the peptides from the reporter groups, but has better water solubility and ionisation ability, making it more amenable for mass spectrometry analysis.
This Fmoc protected spacer is available in crystalline form and can be stored at 4C for up to two years without significant decomposition.
Fmoc-Ebes-OH is available through AnaSpec, a California-based provider of integrated proteomics.
