Protein kinases are a transferase family of self-regulatory enzymes that catalyse the phosphorylation of other proteins by covalently attaching phosphate groups to them, using ATP as a phosphate donor
Reversible protein phosphorylation-dephosphorylation has a principal role in the regulation of essentially all cellular functions and most aspects of cell life, and phosphorylation by protein kinases is a major signal transduction mechanism that regulates gene expression, proliferation, membrane transport, cell metabolism and many other cellular functions by modifiying other proteins.
To successfully assay protein kinase activity, signal transduction mechanisms, protein functions, protein detection, and many other applications, AnaSpec, a provider of integrated proteomics solutions, offers one of the world's largest collections of protein kinase substrates.
This includes phosphorylated, non- phosphorylated, biotinylated, Fret-labelled, and dye-labelled with AnaSpec's high-performance HiLyte Fluor dyes and classic dyes like Fam and Tamra.
