Anti-Actin antibodies stain smooth muscle cells in vessel walls, gut wall, myometrium, myoepithelial cells, and is reactive with tumours arising from smooth muscles and myoepithelial cells
AnaSpec has introduced a suite of labelled and unlabelled anti-Actin antibodies.
Labelling options include biotin, conventional fluorescent dyes, and AnaSpec's proprietary line of HiLyte dyes.
Actin is a highly conserved protein of approximately 42-kDa, expressed in all eukaryotic cells.
Actin filaments are constituents of the cytoskeleton and play essential roles in regulating cell shape, cell division, cell junctions, cell signaling, and movement.
Actins are divided into three classes - alpha, beta and gamma.
At least six Actin isotypes have been identified in mammalian cells.
Alpha Actins are found in muscle (a-skeletal, a-aortic smooth, a-cardiac, and andgamma;2-enteric smooth).
Beta and gamma isoforms are prominent in non-muscle cells.
Smooth muscle a-Actin is important because its expression is mostly detected in vascular smooth muscle cells.
