BioTek Instruments and Gyrasol Technologies have announced a arrangement to promote the application of Gyrasol's Sensor on BioTek's Synergy 4 with hybrid technology multi-mode microplate reader.
The Gyrasol Sensor detection platform screens for kinases and phosphatases in a homogeneous format, providing readouts for phosphorylation events on a variety of biologically relevant substrates.
The assay platform has a high tolerance to ATP (up to 1 uM) and substrate (up to 200 uM), allowing for identification of ATP or substrate-competitive inhibitors.
For many kinases, the assays can be performed in kinetic as well as end-point mode, thus simplifying assay optimisation and the determination of inhibitor modes of action.
BioTek's Synergy 4 hybrid microplate reader combines sensitive filter based and flexible quadruple monochromator-based fluorescence detection technology in one compact unit.
Using hybrid technology, customers are offered flexibility and true multi-detection for an unlimited number of current and future microplate-based assays.
In addition, Synergy 4 includes fluorescence intensity, luminescence, fluorescence polarization, time-resolved fluorescence and UV-visible absorbance.
