Experts from Freeman Technology and Rutgers University will present a powder flow session at a pharmaceutical training event taking place from 27 April to 1 May in Puerto Rico.
Tim Freeman, director of operations for Freeman Technology, will join Professor Fernando Muzzio of Rutgers University in leading the half-day session at this year's Pharmaceutical Technology School.
Course content is delivered by academic experts from Rutgers University, as well as by recognised industry leaders including: Freeman Technology, Capsugel, Glatt Air Techniques, MCC and Tunnell Consulting.
The programme is structured to assist those working in product and process design, manufacturing, scale-up, technology transfer and control.
Beginning with an introduction to QbD, ICH Q8, Q9 and Q10, the course moves through the following topics: identifying critical-to-quality attributes and critical process parameters; sampling, blending and segregation; agglomeration and overlubrication; powder flow; capsule filling; roller compaction; tableting; wet granulation; fluid bed processing; pan coating.
The final day closes with a look at case studies in continuous manufacturing.
'Using measurements made with the FT4 powder tester, together with the processing experience that resides within each company, it is possible to achieve real compatibility between powder and plant, and enable process optimisation - all of which supports the aims of QbD,' said Tim Freeman.
Freeman's FT4 powder tester performs a range of methodologies, measuring shear, bulk and dynamic properties in a short time, using relatively small amounts of material.
The results often indicate why some formulations are 'easy' to manufacture and others are not.
This knowledge is the foundation of efficient processing, and informs the development of formulations that will interact smoothly with the performance characteristics of a plant.